The Connection Between Oxidative Stress and Heart Failure
The heart is a hard-working muscle. Each day it beats approximately 100,000 times without any breaks. It’s been estimated that over the course of an average lifetime, the human heart will beat more than 2.5 billion times.
Heart cells depend on healthy mitochondria to constantly generate the energy they need. But mitochondria aren’t perfect. As they generate cellular energy, mitochondria also contribute to a type of cellular stress called “oxidative stress” by producing reactive oxygen species, or ROS. When energy production kicks into high gear, ROS production also increases and leads to higher levels of oxidative stress.
More studies keep coming out about the damaging results of oxidative stress and how the effects can be slowed or reversed by NRF1, NRF2 and NAD.